Detalhe da pesquisa
1.
Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1.
Proc Natl Acad Sci U S A
; 118(20)2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33975947
2.
Heme Detoxification in the Malaria Parasite: A Target for Antimalarial Drug Development.
Acc Chem Res
; 54(11): 2649-2659, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33982570
3.
Novel hydrazone derivatives of N-amino-11-azaartemisinin with high order of antimalarial activity against multidrug-resistant Plasmodium yoelii nigeriensis in Swiss mice via intramuscular route.
Bioorg Med Chem Lett
; 58: 128522, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34974111
4.
Structure-activity and structure-property relationship studies of spirocyclic chromanes with antimalarial activity.
Bioorg Med Chem
; 57: 116629, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35091169
5.
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Nature
; 538(7625): 344-349, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27602946
6.
Anti-plasmodial activity of aqueous neem leaf extract mediated green synthesis-based silver nitrate nanoparticles.
Prep Biochem Biotechnol
; 52(1): 99-107, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-33890844
7.
A Review of Modifications of Quinoline Antimalarials: Mefloquine and (hydroxy)Chloroquine.
Molecules
; 27(3)2022 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164267
8.
Nonbisphosphonate inhibitors of Plasmodium falciparum FPPS/GGPPS.
Bioorg Med Chem Lett
; 41: 127978, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33766764
9.
Design, synthesis and biological evaluation of mono- and bisquinoline methanamine derivatives as potential antiplasmodial agents.
Bioorg Med Chem Lett
; 38: 127855, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33609655
10.
Novel naphthyl based 1,2,4-trioxanes: Synthesis and in vivo efficacy in the Plasmodium yoelii nigeriensis in Swiss mice.
Bioorg Med Chem Lett
; 51: 128372, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547418
11.
Synthesis of novel 1,2,4-trioxanes and antimalarial evaluation against multidrug-resistant Plasmodium yoelii nigeriensis.
Bioorg Med Chem Lett
; 49: 128305, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34365007
12.
Antimalarial activity of 2,6-dibenzylidenecyclohexanone derivatives.
Bioorg Med Chem Lett
; 47: 128216, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157390
13.
Novel molecule combinations and corresponding hybrids targeting artemisinin-resistant Plasmodium falciparum parasites.
Bioorg Med Chem Lett
; 39: 127884, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33636304
14.
Quest for a potent antimalarial drug lead: Synthesis and evaluation of 6,7-dimethoxyquinazoline-2,4-diamines.
Bioorg Med Chem
; 33: 116018, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33524940
15.
Structure-activity relationship and molecular modelling studies of quinazolinedione derivatives MMV665916 as potential antimalarial agent.
Bioorg Med Chem
; 51: 116513, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34798379
16.
A trio of quinoline-isoniazid-phthalimide with promising antiplasmodial potential: Synthesis, in-vitro evaluation and heme-polymerization inhibition studies.
Bioorg Med Chem
; 39: 116159, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33895706
17.
Preparation, biological & cheminformatics-based assessment of N2,N4-diphenylpyrimidine-2,4-diamine as potential Kinase-targeted antimalarials.
Bioorg Med Chem
; 46: 116348, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34479064
18.
Microwave-assisted synthesis of hybrid PABA-1,3,5-triazine derivatives as an antimalarial agent.
J Biochem Mol Toxicol
; 35(9): e22860, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34313355
19.
In silico study, synthesis, and evaluation of the antimalarial activity of hybrid dimethoxy pyrazole 1,3,5-triazine derivatives.
J Biochem Mol Toxicol
; 35(3): e22682, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33332673
20.
Synthesis of [15,15,15-2H3]-Dihydroartemisinic Acid and Isotope Studies Support a Mixed Mechanism in the Endoperoxide Formation to Artemisinin.
J Nat Prod
; 84(7): 1967-1984, 2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34137611